vanquish - Variant Quality Investigation Helper
Imports Variant Calling Format file into R. It can detect
whether a sample contains contaminant from the same species. In
the first stage of the approach, a change-point detection
method is used to identify copy number variations for
filtering. Next, features are extracted from the data for a
support vector machine model. For log-likelihood calculation,
the deviation parameter is estimated by maximum likelihood
method. Using a radial basis function kernel support vector
machine, the contamination of a sample can be detected.
